The town of Termez, today the regional centre of Surkhandarja, was founded at the crossroads of the caravan route that led from Europe through Central Asia to India in the 2nd -1st century BC. Later it played a great role on the Silk Road route, which went on to China. Already in the 1st century before our time, during the Great Kushan reign, the city expanded to 500 hectares. On the territory of “the Old Termese” a large number of the most interesting objects were discovered. Not far from Termez an ancient settlement was found, which already existed in the period of Greco-Bactria (3.-2. century B.C.). One of the numerous finds discovered in Termez is the Kara-Tepe Buddhist religious centre with various monuments of Buddhist culture.